After approving Qsymia (Phentermine and Topiramate) and Belviq (Lorcaserin) for helping people lose weight a few years ago, FDA recently approved another weight loss medication – Contrave, a combination of the popular antidepressant and smoking cessation drug, Bupropion along with Naltrexone, a medication used in opioid addiction.
Bupropion/naltrexone is approved for obesity defined as a body mass index of 30 or more. The weight loss drug Contrave is marketed in the United States in a sustained release formulation under the name Contrave by Takeda for the drug’s developer, Orexigen Therapeutics.
Bupropion/naltrexone is a combination of two existing FDA approved drugs, bupropion and naltrexone both of which have individually shown some evidence of effectiveness in weight loss, and the combination is expected to have a synergistic effect just like the other combination medications such as Qsymia(Phentermine and Topiramate).
How effective is Contrave?
In clinical trials, patients taking Contrave combined with diet and exercise lost more weight than patients taking a placebo and following the same diet and exercise program averaging about 5% of their body weight. This compares well with 3% body weight seen with Belviq although a bit less than the 9% seen in Qsymia.
Dosing of Cintrave
The recommended daily dose of Contrave is two (8 mg naltrexone/90 mg bupropion) tablets taken twice daily (4 tablets total – 32 mg naltrexone, 360 mg bupropion). Upon initiation, the drug will be started with a quarter-dose (or one tablet) for one week and a pill will be added to the regimen each week until the full recommended dose is reached on Week 4.
Price of Contrave
Compared to the other new weight loss medications, Belviq and Qsymia, Contrave is a bit more affordable costing about 0-$30 dollars per month depending on insurance coverage. With no insurance coverage, it only costs about $100.00 per month with a coupon.
Safety and Side Effects of Contrave
Adverse reactions to Contrave
The most common adverse reactions reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.
According to Dr Prab R. Tumpati, MD – a leading weight loss physician and founder of W8MD Medical Weight Loss Centers of America, Contrave is a valuable tool in fighting obesity that affects over a third of the entire population of the United States with significant morbidity and mortality contributing to 50 other medical problems.
Locations for Contrave
W8MD Medical Weight Loss Centers of America is one of the first weight loss programs to start offering Contrave for eligible patients to help lose weight and is available at their weight loss locations in New York, Pennsylvania and New Jersey. Call W8MD today at 1-800-W8MD-007 to learn more or to setup a consultation.
As one of the very few medical weight loss centers that accepts health insurance for the physician weight loss visits, W8MD gets patients from far and near including other states!
Philadelphia Insurance Weight Loss & Sleep Center: 1718, Welsh Rd, Philadelphia, PA, 19115 Ph: 1-215-676-2334
King Of Prussia Weight Loss & Sleep Center: 987 Old Eagle School Rd, Ste 712, Wayne, PA, 19087 Ph: 215-676-2334
2632 E 21st St Brooklyn New York 11235
W8MD weight loss program in New Jersey.
W8MD weight loss, sleep and medical aesthetics
140 E Evesham Rd Cherry Hill New Jersey 08003